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MDL 3043Personal Injury

Acetaminophen - ASD/ADHD Products Liability Litigation

The causation theory posits that acetaminophen exposure during pregnancy may interfere with fetal neurodevelopment through mechanisms such as oxidative stress, hormonal disruption, or neuroinflammation. Scientific evidence includes epidemiological associations, experimental mechanistic studies, and biological plausibility supported by biomarkers and animal models. The July 2024 Daubert ruling restricts admissible causation evidence to peer-reviewed epidemiological data, mechanistic studies, and authoritative medical conclusions, excluding unreliable expert opinions.

NYSCote, Denise L.Master docket 1:22-md-3043Source: JPML · Updated July 1, 2026

58

Pending actions

722

Total actions filed

Active

Status

10/05/2022

Established

Who qualifies

Plaintiffs must demonstrate prenatal exposure to acetaminophen during pregnancy, particularly in the second and third trimesters. Evidence should include medical records of maternal use, timing of exposure, and biological plausibility. The recent Daubert ruling excludes general causation expert testimony that does not meet reliability standards, emphasizing epidemiological studies, biological mechanisms, and authoritative medical organization conclusions. Plaintiffs must establish that their child's ASD or ADHD was caused by this exposure, supported by peer-reviewed studies, mechanistic data, and consistent findings.

Products involved

  • acetaminophen
  • Tylenol

Alleged injuries

  • autism spectrum disorder (ASD)
  • attention deficit hyperactivity disorder (ADHD)

This page is generated from the official JPML pending-MDL report and public court records, refreshed monthly. It is provided for attorney reference and is not legal advice.

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